Your microbiome reaches further than you think.
From your brain to your skin, the gut is your body's most connected system. A thriving microbiome does not just support digestion — it drives whole-body health.
The gut-brain axis is a two-way communication highway. Beneficial gut bacteria help produce serotonin and other neurotransmitters that influence focus, mood, and sleep quality.
Read the researchMore than 70% of your immune system lives in your gut. A diverse microbiome trains immune cells, reduces chronic inflammation, and keeps your defences sharp.
Read the researchGut bacteria ferment dietary fibre into butyrate and acetate — clean fuel that regulates blood sugar, reduces cravings, and supports steady energy throughout the day.
Read the researchYour microbiome produces the short-chain fatty acids that line, protect, and regulate your digestive system. A balanced gut means less bloating, better regularity, and a stronger intestinal barrier.
Read the researchThe gut-skin axis links microbial balance to skin clarity. A healthy microbiome lowers systemic inflammation and supports the nutrient absorption your skin depends on.
Read the researchMore than 70% of your immune system lives in your gut. A diverse microbiome trains immune cells, reduces chronic inflammation, and keeps your defences sharp.
Read the research38TERA Philosophy
A microbiome-first standard for modern health.
Too many products rely on borrowed language, under-dosed formulas, and scientific decoration. We exist as a response to that drift.
Microbiome-first
Every 38TERA® formula is built around one principle — nourish the ecosystem that feeds everything else.
Clinically reasoned
Each formula is shaped by evidence, clinical judgment, and meaningful ingredient levels rather than decorative label language.
Quality verified
Accredited manufacturing, third-party testing, and transparent standards are part of the product philosophy, not post-rationalized extras.
Built for real life
The goal is not scientific theatre. The goal is to translate good science into something clear, useful, and repeatable in daily health practice.
Evidence-based. Clinically dosed. No shortcuts.
"When you look after the microbiome, you are supporting one of the body's most foundational systems — and when that system thrives, so does everything built on top of it."
Dr. Will Bulsiewicz, MD, MSCI
Co-founder and clinical voice behind the microbiome-first formulation philosophy.
Simon Hill, MSc
Co-founder and nutrition science communicator helping shape how the evidence is translated for daily life.
Scientific studies
The research should be easy to find. And hard to dismiss.
The science behind 38TERA® is informed by peer-reviewed research across prebiotic diversity, resistant starch, polyphenols, digestive function, and the broader microbiome-health relationship.
DMN™ relevant published studies
The studies that connect most directly to the formulation, ingredient logic and outcomes currently shaping the DMN™.
DMN™ relevant published studies
The studies that connect most directly to the formulation, ingredient logic and outcomes currently shaping the DMN™.
Actazin® green kiwifruit powder consumption at 600mg per day for 28 days improves stool form and relieves occasional constipation.
RCT in healthy adults OPEN STUDYKiwifruit-derived supplements increase stool frequency in healthy adults.
Double-blind RCT OPEN STUDYManipulation of Gut Microbiota Using Acacia Gum Polysaccharide.
Mechanistic review OPEN STUDYThe Potential Benefits of Red Beetroot Supplementation in Health and Disease.
Narrative review OPEN STUDYMango Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits.
Narrative review OPEN STUDY
RCE relevant published studies
The studies that connect most directly to the formulation, ingredient logic and outcomes currently shaping the RCE.
RCE relevant published studies
The studies that connect most directly to the formulation, ingredient logic and outcomes currently shaping the RCE.
Magnesium Oxide in the Treatment of Chronic Constipation
Double-Blind, Randomised, Placebo-Controlled Study OPEN STUDYMagnesium Oxide vs Senna for Chronic Constipation
Double-Blind Randomised Controlled Trial. OPEN STUDYMagnesium Oxide for Functional Constipation
Evidence-Based Recommendations OPEN STUDYBritish Dietetic Association Dietary Management Guidelines for Chronic Constipation in Adults.
Clinical Practice Guideline OPEN STUDYAGA-ACG Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation
Clinical Practice Guideline OPEN STUDYA Randomised, Double-Blind, Placebo-Controlled Study of GinFort® in Subjects with Functional Dyspepsia
A Randomised, Double-Blind, Placebo-Controlled Study OPEN STUDYEffects of Ginger on Gastric Emptying and Motility in Healthy Humans
Randomized Controlled Trial OPEN STUDYEffect of Ginger on Gastric Motility and Symptoms of Functional Dyspepsia
OPEN STUDYEffects of Lacticaseibacillus paracasei 327 Intake on the Intestinal Environment
A Randomised, Double-Blind, Placebo-Controlled Trial OPEN STUDYEffects of Heat-Killed Lactobacillus casei 327 on Defecation in Healthy Volunteers
A Randomised, Double-Blind, Placebo-Controlled Study OPEN STUDY
Gut Health & the Microbiome
The studies behind how a balanced microbiome protects the gut lining, supports digestion, and produces the compounds your body depends on.
Gut Health & the Microbiome
The studies behind how a balanced microbiome protects the gut lining, supports digestion, and produces the compounds your body depends on.
Short-Chain Fatty Acids Are Key Mediators of the Favorable Effects of the Mediterranean Diet on Intestinal Barrier Integrity.
Randomised controlled trial OPEN STUDYThe Intestinal Microbiota and the Role of Short-Chain Fatty Acids in Gut Health.
Review of human evidence OPEN STUDYGut Microbiota Composition and Functional Changes in Inflammatory Bowel Disease and Irritable Bowel Syndrome.
Narrative review OPEN STUDYLeaky Gut: Mechanisms, Measurement and Clinical Implications in Humans.
Narrative review OPEN STUDY
The Gut-Brain Axis
The research linking gut microbiome balance to cognitive function, mood regulation, and mental clarity.
The Gut-Brain Axis
The research linking gut microbiome balance to cognitive function, mood regulation, and mental clarity.
Effect of Gut Microbiome Modulation on Muscle Function and Cognition: The PROMOTe Randomised Controlled Trial.
Randomised controlled trial OPEN STUDYDietary Fibre and the Gut-Brain Axis: Microbiota-Dependent and Independent Mechanisms of Action.
Review of human evidence OPEN STUDYThe Microbiota-Gut-Brain Axis.
Narrative review OPEN STUDYAssociations of Neurotransmitters and the Gut Microbiome with Emotional Symptoms across the Menstrual Cycle.
Human observational study OPEN STUDYNeurotransmitter Modulation by the Gut Microbiota.
Narrative review OPEN STUDY
Gut Microbiome & Immune Function
The clinical evidence showing how gut microbial diversity shapes immune cell activity and systemic inflammation.
Gut Microbiome & Immune Function
The clinical evidence showing how gut microbial diversity shapes immune cell activity and systemic inflammation.
The Gut Microbiota Is Associated with Immune Cell Dynamics in Humans.
Human observational study OPEN STUDYGut-Microbiota-Targeted Diets Modulate Human Immune Status.
Randomised controlled trial OPEN STUDYImpact of Dietary Fiber on Inflammation in Humans.
Meta-analysis of RCTs OPEN STUDYInteraction between Microbiota and Immunity in Health and Disease.
Narrative review OPEN STUDY
Microbiome, Metabolism & Energy
Human trials and multi-omics studies revealing how gut bacteria regulate blood sugar, insulin sensitivity, and energy metabolism.
Microbiome, Metabolism & Energy
Human trials and multi-omics studies revealing how gut bacteria regulate blood sugar, insulin sensitivity, and energy metabolism.
Gut Microbial Carbohydrate Metabolism Contributes to Insulin Resistance.
Human multi-omics study OPEN STUDYTransfer of Intestinal Microbiota from Lean Donors Increases Insulin Sensitivity in Individuals with Metabolic Syndrome.
Randomised controlled trial OPEN STUDYHost-Diet-Gut Microbiome Interactions Influence Human Energy Balance.
Randomised controlled trial OPEN STUDYThe Impact of the Gut Microbiota on Human Health: An Integrative View.
Narrative review OPEN STUDY
The Gut-Skin Axis
The emerging clinical evidence connecting gut microbiome balance to skin inflammation, barrier function, and skin health outcomes.
The Gut-Skin Axis
The emerging clinical evidence connecting gut microbiome balance to skin inflammation, barrier function, and skin health outcomes.
The Gut-Skin Axis: A Bidirectional, Microbiota-Driven Relationship with Therapeutic Implications.
Narrative review OPEN STUDYThe Gut Microbiome as a Major Regulator of the Gut-Skin Axis.
Narrative review OPEN STUDYImpact of Gut Microbiome on Skin Health: Gut-Skin Axis Observed through the Lenses of Therapeutics and Skin Diseases.
Review of human evidence OPEN STUDYGut-Skin Axis: Current Knowledge of the Interrelationship between Microbiome and Skin Diseases.
Narrative review OPEN STUDYThe Weekly Digest
Expert insights, microbiome science, and practical advice — no fads, no fear.
