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GI DOCTOR-FORMULATED
Slower gastric emptying changes everything downstream. Harder stool. Bloating. Nausea.
RCE™ supports all three.
GLP-1 medications can be life-changing — but the digestive side effects are real. RCE was formulated to address not just the constipation, but the nausea and bloating too. Because you shouldn't have to sacrifice your gut comfort in order to achieve your health goals.
THE GLP-1 REALITY
GLP-1s act on appetite.
The gut still needs support.
Slowing gastric emptying is part of how GLP-1 medications reduce hunger. That same mechanism changes the gut's entire downstream environment. Transit slows. Stool hardens. Food sitting longer in the stomach creates fullness and nausea. The gut microbiome — sensitive to shifts in motility — changes alongside it.
These effects don't resolve on their own. And they're among the most common reasons people adjust or stop their dose. RCE™ was built for exactly this picture.
Clinical Evidence
Three GLP-1 side effects. Three ingredients. All backed clinical evidence.
Every mechanism in RCE is dosed to published clinical trial evidence — specific to the digestive friction GLP-1 medication creates.
68–70%
Improvement in spontaneous bowel movements — the primary symptom GLP-1 users report.
64%
Elimination of post-meal fullness and bloating — driven by the same delayed gastric emptying GLP-1 causes.
Day 14
Measurable microbiome shift — supporting the gut environment that regular transit depends on.
Plenibiotic™ · RCT 2024 →
The Formula
Three ingredients. Three mechanisms. Each working on a different root cause.
Most products address one symptom. RCE™ is built around the three places GLP-1 medications create digestive friction — at doses matched to the clinical evidence.
Magnesium Oxide
430 mg
Osmotic ReliefGently draws water into the bowel, softening stool and restoring the body's natural urge to go — without cramping, urgency, or stimulant effects.
GinFort® Ginger Extract
200 mg
Gut rhythm + ComfortConcentrated ginger extract standardized to >26% gingeroids. Activates the gut's own motility signals — easing post-meal fullness, bloating, and nausea.
Plenibiotic™
50 mg
Microbiome RestorationShifts the microbial balance toward beneficial, SCFA-producing bacteria. Measurable microbiome change by Day 14. Shelf-stable. No refrigeration.
RCE
Rated 4.2 out of 5 stars
55 Reviews
Daily microbiome nutrition, formulated by a gastroenterologist.
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How RCE™ unfolds
From first dose to lasting regularity.
Within the first hour
Ginger gets things moving
Within the first hour
Ginger gets things moving
GinFort™ gingeroids begin supporting gastric emptying and easing post-meal nausea.
Overnight
Osmosis active
Overnight
Osmosis active
Magnesium oxide draws water into the bowel, softening stool by morning.
Day 7
All three mechanisms online
Day 7
All three mechanisms online
Plenibiotic™ begins contributing to bowel rhythm. Regularity becomes more consistent.
Day 14
Microbiome shifts
Day 14
Microbiome shifts
SCFA-producing bacteria rise. The gut environment supports consistent regularity.
Ongoing
Add DMN®
Ongoing
Add DMN®
RCE™ supports motility. DMN® conditions the broader microbiome. Together, they support the foundations of a healthy gut.
Informed choice
How RCE™ compares.
Built to work with the gut's own mechanisms — not override them.
RCE
Osmotic laxatives
Stimulant laxatives
Magnesium alone
Mechanisms addressed
3
1
1
1
G.I Doctor-formulated
Yes
-
-
-
Formulated for GLP-1 users
Yes
Addresses nausea + bloating
Yes
Habit-forming
No
No
Yes
No
Supports gut microbiome balance
Yes
Side effects
None
Bloating, gas
Cramping, dependence
Limited efficacy
Start RCE.
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- Gastroenterologist-Formulated
- NSF Certified for Sport®
- Third-Party Tested
- Non-GMO
- 30-Day Money-Back Guarantee
FAQS
GLP-1 and RCE — answered directly.
Can I take RCE with a GLP-1 medication?
Yes. RCE was formulated to address the digestive side effects of GLP-1 medications — constipation, bloating, and nausea. Dosing protocol: 1 capsule 20–30 minutes before meals, starting with your largest. Build to 2–3 meals/day as tolerated. Maximum 4 capsules daily. Always consult your prescribing physician.
Will RCE interfere with how my GLP-1 works?
No. RCE works on the gut — not on the GLP-1 mechanism. Magnesium oxide, GinFort™, and Plenibiotic™ act on transit, motility, and the microbiome environment. None interact with the appetite or glycemic pathways your medication acts on. Talk to your prescribing physician if you have specific concerns.
How quickly will I notice a difference?
GinFort™ activates within the first hour — post-meal nausea and fullness ease quickly. Magnesium oxide works overnight; most people notice a shift by morning. All three mechanisms are contributing by Day 7. Microbiome shifts are measurable by Day 14.
Is RCE habit-forming?
No. RCE is non-habit-forming and stimulant-free. It works with the body's natural mechanisms — osmotically, through motility signaling, and by conditioning the gut environment — not by overriding them.
What happens when I taper off my GLP-1?
RCE works on the gut independently of whether you're on a GLP-1. Many people continue with RCE™ post-taper for ongoing regularity, and add DMN™ for broader microbiome conditioning.
How is RCE different from GLP-1 multivitamins?
Multivitamins address nutrient gaps. They don't address why GLP-1 users become constipated, bloated, or nauseated. RCE™ is built around three mechanisms that act on the specific digestive friction GLP-1 medications create.
How long should I take it?
DMN™ is designed as a daily foundation. Like sleep or nutrition, benefits build with consistency.
What does it taste like?
Wild Berry. It's pleasant and easy to drink — just tear, pour into water, and stir. No artificial sweeteners, no chalky texture. Most people genuinely enjoy it as part of their morning routine.
Is it safe for long-term use?
Yes. DMN™ is formulated and tested for daily, ongoing use. It's NSF Certified for Sport, third-party tested for over 100 substances, and made in a GMP and FDA-accredited facility.
How quickly will my Kickstart ship?
Orders typically ship within 2-3 business days. You'll receive a tracking number via email once your order ships. Most customers in the continental US receive their Kickstart within 4-6 business days. We want you to start your gut health journey as soon as possible.
Can I cancel my subscription anytime?
Absolutely. If you decide to subscribe after your Kickstart, you can cancel, pause, or modify your subscription at any time through your account dashboard or by contacting our support team. There are no cancellation fees or penalties. We're here for the long term, but only if DMN™ is working for you.