GI DOCTOR-FORMULATED

GLP-1 slows your gut. RCE™ gets it moving again.

Slower gastric emptying changes everything downstream. Harder stool. Bloating. Nausea.
RCE™ supports all three.

Start with RCE — Save 25%
HSA/FSA via Truemed Third-party tested Gastroenterologist-Formulated Non-habit-forming No stimulant laxatives
GLP-1 medications can be life-changing — but the digestive side effects are real. RCE was formulated to address not just the constipation, but the nausea and bloating too. Because you shouldn't have to sacrifice your gut comfort in order to achieve your health goals.

Dr. Will Bulsiewicz, MD MSCI · Co-Founder, 38TERA & Board-Certified Gastroenterologist

THE GLP-1 REALITY

GLP-1s act on appetite.
The gut still needs support.

Slowing gastric emptying is part of how GLP-1 medications reduce hunger. That same mechanism changes the gut's entire downstream environment. Transit slows. Stool hardens. Food sitting longer in the stomach creates fullness and nausea. The gut microbiome — sensitive to shifts in motility — changes alongside it.

These effects don't resolve on their own. And they're among the most common reasons people adjust or stop their dose. RCE™ was built for exactly this picture.

GLP-1 Digestive Support

DOSING PROTOCOL

A dosing approach built around how GLP-1s work.

For GLP-1 users, Dr. B recommends timing doses to meals — where friction is highest.

  • 1 capsule, 20–30 mins before your largest meal
  • Add as needed before meals, maximum 4 capsules daily
  • Once symptoms settle, add DMN® to strengthen the microbiome behind your results.

Clinical Evidence

Three GLP-1 side effects. Three ingredients. All backed clinical evidence.

Every mechanism in RCE is dosed to published clinical trial evidence — specific to the digestive friction GLP-1 medication creates.

68–70%

Improvement in spontaneous bowel movements — the primary symptom GLP-1 users report.

Magnesium Oxide · RCTs 2019 & 2021

64%

Elimination of post-meal fullness and bloating — driven by the same delayed gastric emptying GLP-1 causes.

GinFort® RCT, 2022 →

Day 14

Measurable microbiome shift — supporting the gut environment that regular transit depends on.

Plenibiotic™ · RCT 2024 →

The Formula

Three ingredients. Three mechanisms. Each working on a different root cause.

Most products address one symptom. RCE™ is built around the three places GLP-1 medications create digestive friction — at doses matched to the clinical evidence.

Magnesium Oxide

430 mg

Osmotic Relief

Gently draws water into the bowel, softening stool and restoring the body's natural urge to go — without cramping, urgency, or stimulant effects.

GinFort® Ginger Extract

200 mg

Gut rhythm + Comfort

Concentrated ginger extract standardized to >26% gingeroids. Activates the gut's own motility signals — easing post-meal fullness, bloating, and nausea.

Plenibiotic™

50 mg

Microbiome Restoration

Shifts the microbial balance toward beneficial, SCFA-producing bacteria. Measurable microbiome change by Day 14. Shelf-stable. No refrigeration.

How RCE™ unfolds

From first dose to lasting regularity.

Within the first hour
Ginger gets things moving

GinFort™ gingeroids begin supporting gastric emptying and easing post-meal nausea.

Overnight
Osmosis active

Magnesium oxide draws water into the bowel, softening stool by morning.

Day 7
All three mechanisms online

Plenibiotic™ begins contributing to bowel rhythm. Regularity becomes more consistent.

Day 14
Microbiome shifts

SCFA-producing bacteria rise. The gut environment supports consistent regularity.

Ongoing
Add DMN®

RCE™ supports motility. DMN® conditions the broader microbiome. Together, they support the foundations of a healthy gut.

Informed choice

How RCE™ compares.

Built to work with the gut's own mechanisms — not override them.

RCE
Osmotic laxatives
Stimulant laxatives
Magnesium alone
Mechanisms addressed

3

1
1
1
G.I Doctor-formulated

Yes

-
-
-
Formulated for GLP-1 users

Yes

Addresses nausea + bloating

Yes

Habit-forming

No

No
Yes
No
Supports gut microbiome balance

Yes

Side effects

None

Bloating, gas
Cramping, dependence
Limited efficacy
The Complete Gut Protocol

Start with RCE. Build with DMN®.

RCE gets you regular. DMN™ keeps your microbiome thriving. Together, they support the foundations of a healthy gut.

FAQS

GLP-1 and RCE — answered directly.