DMN®

Consumption of Solnul® resistant potato starch produces a prebiotic effect in a randomized, placebo-controlled clinical trial. 
Nutrients 2023; 15(7), 1582.

Resistant potato starch supplementation reduces serum histamine levels in healthy adults with links to attenuated intestinal permeability.
Journal of Functional Foods Volume 108, September 2023, 105740

• Dose provided in the amount proven in human clinical trials.
• Resistant to digestive enzymes, it ferments in the large intestine, nourishing the microbiota.
• A study on 75 healthy adults shows a significant increase in Akkermansia and Bifidobacterium over four weeks with a daily intake of 3.5g of Solnul®.
• Solnul®: sustainably sourced, ancestral, evidence-based, low FODMAP, with proven prebiotic benefits.

Actazin® green kiwifruit powder consumption at 600 mg per day for 28 days improves stool form and relieves occasional constipation in healthy individuals: a randomized controlled trial. 
Bioactive Carbohydrates and Dietary Fibre, 2024;32:100436.

Kiwifruit-derived supplements increase stool frequency in healthy adults: a randomized, double-blind, placebo-controlled study. 
Nutr Res J, 2015; 35:401-408

• Kiwifruit is rich in fiber, multiple polyphenols , digestive enzymes (actinidin), organic acids, vitamins and minerals.
• In two clinical studies, Actazin® 600mg significantly increased weekly bowel movements. 
• On May 7, 2021, the European Food Safety Authority deemed that based on the scientific evidence, green kiwifruit helps in the maintenance of normal defecation. The effect of Actazin® 600mg is functionally equivalent.

2021 study: Actazin® 600mg daily significantly increased Faecalibacterium in mild constipation.

The Efficacy of Gum Arabic in Managing Diseases: A Systematic Review of Evidence-Based Clinical Trials.
Biomolecules. 2023 Jan 9;13(1):138.

Manipulation of Gut Microbiota Using Acacia Gum Polysaccharide.
ACS Omega. 2021 Jul 20; 6(28): 17782–17797.

Acacia Gum is a Bifidogenic Dietary Fibre with High Digestive Tolerance in Healthy Humans.
Microbial Ecology in Health and Disease, 15:1, 43-50.

Adansonia digitata L. (Baobab) Bioactive Compounds, Biological Activities, and the Potential Effect on Glycemia: A Narrative Review.
Nutrients. 2023 May; 15(9): 2170.

A Pectin-Rich, Baobab Fruit Pulp Powder Exerts Prebiotic Potential on the Human Gut Microbiome In Vitro.
Microorganisms. 2021 Sep 17;9(9):1981.

• A blend of two ancestral soluble dietary fibers, Acacia and Baobab. 
• Source of bioactives such as gallic acid, (-)-epicatechin, epicatechin-3-gallate, procyanidin B2, tannins and carotenoids
• In an ex-vivo simulation of the human intestinal microbial ecosystem, 5g of the combination of Acacia + Baobab were found to exert significant prebiotic activity. The study showed the promotion of beneficial bacteria, including the Bifidobacterium spp., and specific bacteria families such as Akkermansiaceae and Christensenellaceae.Note that the trial was ex vivo and at a different dose, but these results along with other studies support the prebiotic nature of both Baobab and Acacia fiber.
• Certified Low FODMAP.

Lingonberry (Vaccinium vitis-idaea L.) Fruit as a source of bioactive compounds with health promoting effects - a review. 
Int J Mol Sci 2021; 22(10):5126

Lingonberries alter the gut microbiota and prevent low-grade inflammation in high-fat diet fed mice. 
Food Nutr Res 2016;60:29993

Lingonberries and their two separated fractions differently alter the gut microbiota, improve metabolic functions, reduce gut inflammatory properties, and improve brain function in ApoE-/-mice fed high-fat diet. 
Nutr Neurosci 2020;23(8):600-612

• Wildcrafted and hand harvested from certified organic nordic forests.
• Lingonberry boasts the highest polyphenol/antioxidant (ORAC) value among berries.
• Contains polyphenols like proanthocyanidins, catechin, and epicatechin, supporting gut health and metabolic functions.
• Animal model studies indicate that the polyphenols in lingonberries alter the gut microbiota and reduce inflammation.

The Potential Benefits of Red Beetroot Supplementation in Health and Disease.
Nutrients. 2015 Apr; 7(4): 2801–2822.

A review on bioactive compounds of beet (Beta vulgaris L. subsp. vulgaris) with special emphasis on their beneficial effects on gut microbiota and gastrointestinal health
Crit Rev Food Sci Nutr. 2021;61(12):2022-2033.

Effect of two-week red beetroot juice consumption on modulation of gut microbiota in healthy human volunteers - A pilot study.
Food Chem. 2023 Apr 16:406:134989.

• Ideally grown in the fertile soils and cool temperatures of Poland as part of a centuries old food tradition.
• Source of multiple bioactive phytochemicals including betalains, flavonoids, polyphenols, Saponins and inorganic nitrate.
• Research indicates that beets contain a variety of bioactive compounds with the potential to positively alter the gut microbiota.

Mango (Mangifera indica L.) Polyphenols: Anti-Inflammatory Intestinal Microbial Health Benefits, and Associated Mechanisms of Actions.
Molecules. 2021 May; 26(9): 2732.

Mango Supplementation Modulates Gut Microbial Dysbiosis and Short-Chain Fatty Acid Production Independent of Body Weight Reduction in C57BL/6 Mice Fed a High-Fat Diet
J Nutr. 2016 Aug;146(8):1483-91.

Prebiotic effect of predigested mango peel on gut microbiota assessed in a dynamic in vitro model of the human colon (TIM-2).
Food Res Int. 2019 Apr:118:89-95.

• Polyphenols including mangiferin, benzoic acid, gallic acid, gallate, ellagic acid as well as quercetin.
• Several studies indicate that mango polyphenols have prebiotic effects and the potential to lower intestinal inflammation and promote intestinal barrier integrity.